Publications

 

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19.Chen, N. Y*., Lin, CW.*, Lai, T. Y., Wu, C. Y., Liao, P. C., Hsu, T. L., & Wong, C. H. (2024). Increased expression of SSEA-4 on TKI-resistant non-small cell lung cancer with EGFR-T790M mutation. Proc Natl Acad Sci U S A, 121(5), e2313397121. 

18. Song CH, Jeong M, In H, Kim JH, Lin CW, Han KH. (2023) Trends in the Development of Antibody-Drug Conjugates for Cancer Therapy. Antibodies (Basel).12(4):72

17. Lin CW, Han KH (2023) Antibody Libraries as Platforms to Exploring Target and Receptor Pleiotropy. Israel Journal of Chemistry.DOI: 10.1002/ijch.202300050

16. Lin CW, Wang YJ, Hsu TL, Han SY, Wu HC, Shen CN, Dang V, Chen MW, Chen LB, Wong CH. (2021) Homogeneous antibody and CAR-T cell with improved effector functions targeting SSEA-4 glycan on pancreatic cancer. Proc Natl Acad Sci U S A. 2021;118 (50):e2114774118.

15. Lin CW, Zheng T, Grande G, Nanna AR, Rader C, Lerner RA. (2021) A new immunochemical strategy for triple-negative breast cancer therapy. Sci Rep. 2021;11(1):14875.

14. Lin CW, Lerner RA (2021) Antibody libraries as tools to discover functional antibodies and receptor pleiotropism. Int. J. Mol. Sci. 22(8), 4123

13. Lee CD, Watanabe Y, Wu NC, Han J, Kumar S, Pholcharee T, Seabright GE, Allen JD, Lin CW, Yang JR, Liu MT, Wu CY, Ward AB, Crispin M, Wilson IA. (2021) A cross-neutralizing antibody between HIV-1 and influenza virus. PLoS Pathog. 17(3):e1009407

12. Lin CW, Lerner RA. (2020) The Janus-Faced Nature of Cancer Immunity. TheScienceBreaker. (6)392

11. Lin CW, Xie J, Zhang D, Han KH, Grande G, Wu NC, Yang Z, Yea K, Lerner RA. (2020) Immunity against cancer cells may promote their proliferation and metastasis. Proc Natl Acad Sci U S A. 117 (1) 426-431

10. Han KH, Arlian BM, Lin CW, Jin HY, Kang GH, Lee S, Lee PC, Lerner RA. (2020) Agonist Antibody Converts Stem Cells into Migrating Brown Adipocyte-Like Cells in Heart. Cells. 20;9(1), 256.

9. Yang Z. Wan Y, Tao P, Qiang M, Dong X, Lin CW, Yang G, Zheng T, Lerner RA. (2019) A Cell-Cell Interaction Format for Selection of High Affinity Antibodies and Peptides to Membrane Proteins: Gated Ion Channels, ASIC1a, GPCRs, the Opioid Receptor. Proc Natl Acad Sci U S A. 116(30):14971-14978

8. Wu NC, Lv H, Thompson AJ, Wu DC, Ng WWS, Kadam RU, Lin CW, Nycholat CM, McBride R, Liang W, Paulson JC, Mok CKP, Wilson IA. (2019) Preventing an antigenically disruptive mutation in egg based H3N2 seasonal influenza vaccines by mutational incompatibility. Cell Host & Microbe 25(6):836-844

7. Merkouris S, Barde YA, Binley KE, Allen ND, Stepanov AV, Wu NC, Grande G, Lin CW, Li M, Nan X, Chacon-Fernandez P, DiStefano PS, Lindsay RM, Lerner RA, Xie J (2018) Fully human agonist antibodies to TrkB using autocrine cell-based selection from a combinatorial antibody library. Proc Natl Acad Sci U S A. Jul 24;115(30):E7023-E7032

6. Wu NC, Thompson AJ, Xie J, Lin CW, Nycholat CM, Zhu X, Lerner RA, Paulson JC, Wilson IA (2018) A complex epistatic network limits the mutational reversibility in the influenza hemagglutinin receptor-binding site. Nat Commun 9(1):1264

5. Tsai T-I, Li ST, Liu CP, Chen KY, Shivatare SS, Lin CW, Liao SF, Lin CW, Hsu TL, Wu YT, Tsai MH, Lai MY, Lin NH, Wu CY, Wong CH (2017) An Effective Bacterial Fucosidase for Glycoprotein Remodeling. Acs Chem Biol 12(1):63-72

4. Wu C-Y, Lin CW, Tsai TI, Lee CD, Chuang HY, Chen JB, Tsai MH, Chen BR, Lo PW, Liu CP, Shivatare VS, Wong CH (2017) Influenza A surface glycosylation and vaccine design. Proc Natl Acad Sci U S A. 114(2):280-285

3. Yea K, Zhang H, Xie J, Jones TM, Lin CW, Francesconi W, Berton F, Fallahi M, Sauer K, Lerner RA. (2015) Agonist antibody that induces human malignant cells to kill one another. Proc Natl Acad Sci U S A. 112(45):E6158-E6165.

2. Shivatare SS, Chang SH, Tsai TI, Ren CT, Chuang HY, Hsu L, Lin CW, Li ST, Wu CY, Wong CH. (2013) Efficient Convergent Synthesis of Bi-, Tri-, and Tetra-antennary Complex Type N-Glycans and Their HIV-1 Antigenicity. J Am Chem Soc .135(41):15382-15391

1. Hung T-C*, Lin CW*, Hsu T-L, Wu C-Y, & Wong C-H (2013) Investigation of SSEA-4 Binding Protein in Breast Cancer Cells. J Am Chem Soc. 135(16):5934-5937.

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